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Successful Slimming Strategies

by Erika Camardella

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“I WILL lose weight this year."

It may be cliché, but managing weight does start with resolution, whether it’s in January or June. Each year, many people start to think about how they’ll lose weight even before they try wriggling into bathing suits or skinny jeans. Weight loss products and programs can appeal to peoples’ desire to look svelte and shapely for the summer months, but many are over-hyped with confounding catch phrases that tap into consumers’ insecurities. The idea that one can just pop a pill, sit back and wait … for that Baywatch body to magically appear is a ‘wait for loss’ fairy tale. Claims aside, there are nutritional ingredients that may support a real body evolution, but it takes a resolute approach—including changing diet habits, incorporating the right foods, balancing blood glucose, and (yes) burning more calories than you consume. An adjunct weight management product can be that extra ingredient that helps get consumers there.

Appearance is a vanity we cherish, but there are more serious reasons to manage the pounds. Surplus body weight is associated with excess morbidity and mortality.1 Among adults, overweight and obesity elevate the risk of heart disease, diabetes and some types of cancer. They also increase the severity of disease associated with hypertension, arthritis and other musculoskeletal problems.2 Though the terms have been used interchangeably, their meanings are notably different. Overweight refers to an excess of body weight compared to set standards. The excess weight may come from muscle, bone, fat and/or body water, while obesity refers specifically to having an abnormally high proportion of body fat.3

Diet, physical activity, genetic factors, environment and health conditions all contribute to overweight in children and adults.4 The potential health benefits from reduction in the prevalence of overweight and obesity are of significant public health importance. The prevalence of overweight and obesity changed little from the early 1960s to 1980.5 But, findings from the National Health and Nutrition Examination Surveys (NHANES) showed substantial increases in overweight among adults from the late '80s through 2004.6 The upward trend in overweight since 1980 reflects primarily an increase in the percentage of adults aged 20 to 74 years who are obese. In 2004, as in 1960, approximately 33 percent of adults were overweight (body mass index (BMI), of 25 to 29); however, the percentage of obese (BMI > 30) adults increased from 12 to 32 percent. And, even the percentage of children and adolescents who are overweight has risen since the early ’80s.

With obesity and overweight carrying such high statistical numbers, it is easy to understand why diets, which address people’s desire to find ways to instant, no fuss results, come and go. But, successful weight management should include setting reasonable goals of a healthy weight gradually, anticipating roadblocks (holiday treats and feasts),7 and adding movement to burn calories, using weight management supplements as a healthy adjunct. Becoming overweight doesn’t happen overnight; losing weight and managing it doesn’t either.

Consumers acknowledge they are responsible for taking this step towards being responsible for their health, yet are not following through with the necessary lifestyle change. ACNielsen recently reported 82 percent of consumers acknowledge that individuals are the most responsible for weight gain in the U.S. population; but, relatively small percentages of people heed their own awareness of how to manage weight and improve diet. Marcia Mogelonsky, senior analyst for market research firm Mintel, said consumers like to create their own unique diet plan. “Consumers cycle through diet plans with great speed because they are looking for results; if they feel a diet is not working for them, they tend to look for another alternative,” she said. “For many dieters, the most successful plan is one that combines dieting methods. Our society is always looking for a custom solution for good dieting.”

The current market offers a buffet of solutions and, for the most part, manufacturers agree the weight management market is ‘healthy’ or at least in a state of positive flux. As long as obesity is an issue, healthy and effective weight loss products will be sought after. “Consumers remain committed to weight loss, given the fact that it is still one of the biggest markets in the entire supplement category,” said Scott Steil, vice president sales and marketing, Humanetics Corp. “Certain consumers are still looking for that magic pill that causes weight loss while they sleep. However, I believe that this group is shrinking, given the reality that such a product does not exist.”

It’s not just the American market adding an extra notch to its belt to accommodate personal expansion; other continents are also seeing the results of spreading Western diets. According to Paul Dijkstra, executive vice president, InterHealth Nutraceuticals: “We’re also seeing a great deal of growth within this segment in other areas of the world, including parts of Asia where obesity was never a problem before. As their diets become more westernized, many Asians are joining their American counterparts in the battle of the bulge. That, too, is fueling growth.” Kristina Williams, marketing director for Cevena Bioproducts Inc., agreed, pointing out that any decline seen in the weight loss category was likely due to the ephedra ban fall-out; but, with obesity rates climbing in North America and around the world, demand for weight loss products is rising. “This results in weight control becoming increasingly important both from a personal health perspective and also due to its cost to society,” she said. “Even though the overall category of weight loss pills and meal replacements may have shown negative growth in 2005, this was mainly driven by the decline in sales of ephedra products. Non-ephedra products (weight loss pills) grew 25 percent in 2004, and as a manufacturer of a fiber ingredient that can aid in weight loss, we have noticed an increased demand for weight loss applications.”

Anchoring the Basics

Consumers should be made aware of several factors that must be taken into account in order to effectively maintain a healthy weight and not instigate the dips and dives leading to “yo yo” diet failures. “We need to anchor the base things, first and foremost—lifestyle. If we can’t anchor that, nothing will boost the metabolism,” said Rochelle Rice, FRS Health fitness guru, president and owner of In Fitness & In Health, and author of “Real Fitness for Real Women.”

A sensible lifestyle is the key to yearround healthy weight. “Sleep is crucial for total health; at least eight hours a night helps you heal and rejuvenate,” said Ron Udell, president of Soft Gel Technologies. “And the way we deal with stress will affect our health, so it should be managed in a healthful way that includes deep breathing and/or meditation.”

Managing weight is a more complex issue than just losing pounds, explained R.V. Venkatesh, managing director of Gencor Pacific Inc. “Too much weight lost too fast is not good for a person’s physiology,” he said. “More often than not, such sudden losses result from water loss due to diuretic effects of certain weight loss products and there is a high chance of rebound and weight gain.” It is important to ensure gentle and gradual loss of weight (as fat) and ensure lean body mass is maintained, leading to long term benefits.

Calories consumed are calories stored—unless they are put to work in some form of movement. “It concerns and surprises me that weight loss is a $50 billion industry, yet we are still fat,” Rice said. She suggested retailers shift the vernacular in talking with shoppers to emphasize “movement” versus “exercise” and encourage them to take pleasure in the little movements that can be incorporated into everyday lives to keep the calories burning.

Reducing overall calories, replacing sugary drinks with water, and consuming protein-rich, low-fat, low-glycemic foods can be a smart way to fill a grocery cart and keep a body healthy. People from all backgrounds, age and gender can benefit from foods that have a low glycemic index (GI), because as Saul Katz, president of Solo GI Nutrition Inc., explained, choosing foods based on nutritional values as well as glycemic impact controls the “spike and crash” cycles that occur after eating highly processed foods, and also gives a feeling of fullness. He said: “Every cell in the body is designed to use blood sugar as its primary fuel source, provided by the foods we eat. Blood sugar impacts every function in the body, including mental and physical performance, moods, hunger, energy, disease prevention and ultimately the overall health of the body.”

Ingredients to Success

There is help for those battling the bulge. Nutritional ingredients to help achieve success can be found in an array of beverages, foods and dietary supplements and fall under one or more of several methods. Thermogenics turn up the calorie burn while fat and starch blockers target particular compounds in the diet; other ingredients may increase satiety or work to retain lean muscle while losing fat.

Perhaps the hottest current ingredient for weight management is Hoodia gordonii, which originated in the Namib Desert in Southern Africa. Hoodia has been shown to increase adenosine triphosphate (ATP) levels in the hypothalamus, helping to control appetite and decrease food intake by as much as 40 percent.8 ATP, the nucleotide responsible for energy transfer within cells, may play a critical role in this energy sensing and satiety. A research review noted the San hunters of South Africa found hoodia, “when eaten even in small quantities, causes the sensation of hunger to cease.”9 Such tales led South Africa’s Council for Scientific and Industrial Research (CSIR) to investigate the plant’s effects.10

Subsequent animal research demonstrated that an extract from the plant was highly effective in reducing weight. In 1997, CSIR approached the British firm Phytopharm to collaborate in developing the active ingredient, P57, into a prescription drug, but global marketing of P57 is not expected until 2008.11 Various firms are offering hoodia materials or combination products. Flora Inc., for example, combines hoodia with yerba mate, green coffee bean and green tea extract to boost fat burning; Natures Benefit offered one of the first authentic hoodia finished products, while Stella Labs pioneered the ingredient category; Soft Gel Technologies combines hoodia with the specialty ingredient PinnoThin™ (a pine nut extract that increases satiety12) in its Suppresia-HP.

Another succulent used for weight management is prickly pear cactus (Opuntia ficus indica). Prickly pear fiber extract (as NeOpuntia®, from BioSerae Laboratories) binds to fat, resulting in a gellike complex not absorbed by the GI tract, but rather eliminated out of the body.13,14

And an Indian succulent, Caralluma fimbriata, is the exciting new kid in the weight management arena. An extract of the plant (as Slimaluma™, from Gencor Pacific) was successful in suppressing appetite, reducing waist circumference, increasing weight loss and fat loss and dropping BMI.15 Slimaluma is GRAS (generally recognized as safe), Kosher and Halal certified. Venkatesh said, “The herb is used in India to control hunger and is classified as a Famine Food by the Council of Scientific and Industrial Research, India. It has been used as a vegetable for hundreds of years and has a well-established safety profile with no side effects.”

Another botanical ingredient, Garcinia cambogia, promotes a feeling of fullness and has been studied for both appetite suppression and fat loss. Hydroxycitric acid (HCA), extracted from the rind of this yellow pumpkin-shaped fruit, works by diverting carbohydrates away from fat synthesis and toward stored glycogen, thereby signaling satiety and leading to reduced food consumption.16 Super CitriMax®, InterHealth’s patented ingredient containing a unique HCA compound, inhibits the conversion of carbohydrates into fat and promotes an increase in the formation of stored energy as glycogen. The product also signals the brain to turn off hunger signals. Studies show clinical-strength doses of Super CitriMax actually increase fat oxidation and promote healthy levels of serotonin, a neurotransmitter involved in mood, sleep and appetite control that may help address many of the emotional issues overweight people face, including binge-eating and depression.17, 18

Increasing fiber in the diet helps manage weight by creating a feeling of fullness. There is strong epidemiologic support that fiber intake can prevent obesity by decreasing absorption of other macronutrients, such as fat, and changing the body’s gut hormone secretion.19 One type of fiber, glucomannan, comes from the Asiatic konjac root. Glucomannan has the highest molecular weight and viscosity among fibers, and it can generate feelings of satiety.20 In fact, taking glucomannan with a meal may slow carbohydrate absorption and post-meal glucose response by up to 50 percent.21 Another trial found glucomannan taken as a supplement alone significantly increased weight loss in overweight men and women, compared to dieting alone or in combination with guar gum and alginate.22

Beta-glucan, a fiber from barley or oats, is not a new ingredient, but researchers have found novel ways to concentrate betaglucan to make the necessary dosage more convenient without destroying the natural health benefits of the fiber. Williams said in order to achieve multiple health benefits to help promote weight loss, it is important that the soluble fiber is viscous, forming a soft gel in the stomach. Taken before meals, Cevena’s Viscofiber® creates a feeling of fullness and moderates glucose absorption in the body to reduce cravings, helping the body utilize nutrients longer and providing more energy.

Turn up the Heat

Thermogenesis is a process by which the body’s metabolism increases, turning up the burn on calories in brown adipose (fat) cells (BAT). The best-known thermogenic agent in the dietary supplement market currently is Citrus aurantium, or bitter orange. Advantra Z® is a standardized, patented form of bitter orange, with researched benefits including stimulating thermogenesis, reducing weight, increasing the percentage of lean muscle mass in relation to total body mass, improving athletic performance and suppressing appetite.23,24,25 In addition, Advantra Z, even at high doses, has been shown to not impact blood pressure, unlike some other thermogenic agents.26 “There are more than nine studies on more than 200 study participants showing the safety and efficacy of products containing Advantra Z,” said Danielle Thomas, director of sales and marketing for Nutratech Inc.

Bitter orange is increasingly seen in combination weight management products. For example, Weight Management Naturally, from the Healthcare Naturally line (Nature’s Benefit), is a thermogenic formula containing chromium, green tea, Citrus aurantium and green coffee been extract (for its chlorogenic acid content). JavaFit Diet Plus (Javalution Coffee Co.), a fortified gourmet coffee with Garcinia cambogia, bitter orange extract, chromium polynicotinate and extra caffeine is an example of a functional food that caters to the lifestyle trend of weight management. “It was shown in a study to dramatically increase metabolic weight, while other studies showed JavaFit had a greater weight loss, waist size reduction as well as higher decrease of body fat over regular coffee with equal adverse events,” said Gilbertson D. Cuffy, marketing director, Javalution Coffee Co. Inc.

Thermogenesis is also the basis from which dehydroepiandrosterone (DHEA) metabolite 3-acetyl-7- oxodehydroepiandrosterone (also known as 7-oxo-DHEA) functions in weight management. Humanetics currently supplies the patented, researched ingredient called 7-Keto®. Several pre-clinical studies have been performed to look at mechanism of action and toxicology. One study on 7-Keto® in overweight adults as an adjunct to a calorie-restricted diet found it lessened the decline of the resting metabolic rate (RMR) associated with dieting, and increased RMR by 1.4 percent.27 Researchers also noted 7-Keto did not act as a stimulant; rather, it turned up thermogenesis and increased fat-burning enzyme activity. Obese subjects in another study increased weight loss and reduced three times more fat when taking 7-Keto.28 Obese patients given a formula containing 7-Keto along with L-tyrosine, asparagus root extract, choline, inositol, copper, manganese and potassium, for eight weeks increased their weight loss and reduced body mass index (BMI).29 “We have spent millions of dollars on clinical work to not only prove our product works, but works very well at providing significantly more weight loss than diet and exercise alone,” Steil said.

Another botanically-based thermogenic ingredient deemed useful in weight management is green tea. Animal trials suggest green tea can decrease leptin levels and suppress adipose tissue development,30 while other research has theorized it can regulate glucose uptake in fat tissue.31 Some say green tea’s thermogenic action and fat oxidation is due to its caffeine content,32 which is actually low when compared to coffee and black tea. One Japanese study found green tea extract—rich in the flavonoid epigallocatechin gallate (EGCG)—increased endurance capacity, energy metabolism and fat oxidation in mice.33 These potent polyphenols can increase the body fat burn by as much as eight percent, most noticeably if taken after eating a high-fat meal.34

Green tea flavonoids are also a key component in a new healthy energy drink from FRS beverage. Designed by Harvard scientists and the co-founder of Balance Bar, the drink delivers powerful antioxidant protection, increases daily energy and mental focus and safely enhances athletic performance and recovery. Active ingredients include quercetin, which is typically found in the skins of apples and onions, as well as green tea catechins, plus the dietary reference intake (DRI) of seven key vitamins—C, E, B1, B2, B3, B6 and B12.

The Lean on Me

Another form of weight management can be accomplished by shifting the proportion of fat mass to lean muscle. Conjugated linoleic acid (CLA), trims fat and helps maintain lean muscle mass.35 Though CLA’s exact mechanism of action is unknown, it seems to regulate energy expenditure, fatty acid oxidation, lipolysis and lipogenesis.36 One of the leading forms of CLA, Tonalin® CLA from Cognis Nutrition & Health, has several strong human clinicals. In a randomized, double blind, placebo-controlled study of 180 overweight adults, 4.5 g/d of Tonalin CLA decreased body fat mass by up to 9 percent, with increases in lean body mass.37 In a one-year continuation of the study, CLA supplementation maintained lean muscle mass and fat loss, while lowering leptin levels.38 And in late 2006, a study found overweight adults taking 4 g/d of Tonalin CLA for eight months reduced body fat mass by 2.2 pounds and body weight 1.3 pounds, while those on a placebo gained similar quantities.

Several studies have shown the various benefits of Coleus forskholii and its root extract forskolin. A member of the mint family, it grows wild in India, Burma and Thailand. This botanical supplement is used in trading fat for muscle and in optimizing body composition.39,40,41L-carnitine, an amino acid that helps transport fatty acids into the cell’s powerhouse—the mitochondria—for energy production may also influence glucose metabolic rate in skeletal muscle, benefiting lean body mass.42 In 12 slightly overweight adults, 3 g/d of L-carnitine for 10 days significantly increased fat oxidation without affecting protein necessary for muscle growth.43

Banaba (Lagerstroemia specios) works by lowering blood glucose levels44 and regulating adipocytes (fat cells),45,46 and is involved in adipogenesis, the leading mechanism for weight gain and obesity. Banaba has also been associated with treatment of type 2 diabetes and helps stimulate glucose transport.47 The patented ingredient GlucoFit™ (Soft Gel Technologies) contains corosolic acid derived from the banaba plant, clinically proven to help balance blood glucose levels.

What’s Around the Curve?

“From a sales perspective, Hoodia, CLA, green tea and 7-Keto-based products have nicely filled in the post ephedra landscape,” Steil said. “Additionally, products that can help increase metabolism are also a growing category.” Udell noted: “Utilizing the glycemic index and load seem to be gaining momentum along with meal replacement powders, drinks and nutrition bars, and high caffeine consumption, especially in children and teenagers.” And Katz reiterated a growing body of scientific evidence suggests low GI foods have an important and growing role in obesity management by controlling appetite and insulin levels. “It has been documented that low GI foods are slow to digest, providing a feeling of fullness, which in turn has an immediate impact on appetite,” he said.

Another trend to watch is new product formulations that perform a dual purpose, such as weight loss and cholesterol control, likes Iovate’s new weight loss product Cylaris. It contains Cissus quadrangularis (an Indian herb with high amounts of vitamin C, carotene A, anabolic steroidal substances and calcium) and soy as ingredients to maintain healthy cholesterol levels. “It makes sense in that people who need to lose weight also have cholesterol issues—I think we will see more of these combination products in the future,” Thomas said. Another product, Syndrome X Nutritional Factors (Natures Benefit), is designed to assist with weight control by addressing the hallmark problems of metabolic syndrome, blood cholesterol, blood pressure and insulin resistance.

“Insulin is one of the most important causes of obesity itself,” said Stephen Holt, M.D., founder of Natures Benefit. “Insulin resistance leads to excess insulin secretion which has many negative effects on the body. In addition to the inefficient ‘handling’ of blood glucose, insulin excess in the presence of insulin resistance can promote cholesterol synthesis in liver, raise blood pressure, cause other hormonal aberrations and result in cell proliferation.”

A Key Opportunity

According to the Centers for Disease Control (CDC) Division of Nutrition and Physical Activity in Atlanta, “With increasing rates of obesity, nonprescription product use is likely to increase.”48 Natural products retailers can take this key opportunity to help customers achieve their weight loss goals by educating them about supplemental nutritional aids that promote healthy, long-term weight management. Retailers also have the increased responsibility of offering products that are based on sound science and not just hype. “Consumers have become wary of the clutter of fad diets and miracle products and are looking for products that are not only effective but safe,” Cuffy said.

One first step is educating employees on what claims can be made and which ingredients target which kind of weight loss challenge (fat loss, carbohydrate or starch blocker, appetite suppression, etc.) so they can discuss the features and benefits of a product accurately and completely.

Merchandising can be done with end caps for exercise equipment (weights, yoga mats and tapes) interspersed with weight loss supplements alongside written materials on lifestyle weight management tools. If space allows, sponsor a local weight loss practitioner, or practitioners, for evening lectures on weight management. Some manufacturers may offer several educational seminars on their products, including weight-loss products. Approaching manufacturers via their Web site is another good way to get the most current study or information on a product. Being armed with a plateful of up-to-date information on such a timeless and weighty issue can help shoppers choose the right weight management products for them—and help keep the resolve in their resolution throughout the year.

To view the references for this story, click here.


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